Newbridge Road, North Broadway, Jericho-Oyster Bay Road, Pine Hollow Road, South Street

Direction: North/South
Southern Terminus: Jerusalem Avenue (NY 105) in North Bellmore
Northern Terminus: Bay Avenue in Oyster Bay

NY 106 begins as Newbridge Road at NY 105, just south of the Southern Parkway. (It used to extend farther south along Newbridge Road to Merrick Road.) It runs to the northeast until Hicksville, where it is multiplexed with NY 107 as North Broadway. North Broadway runs to the north and has interchanges with the Northern Parkway, the Long Island Expressway (I-495), and Jericho Turnpike (NY 25). Just north of Jericho Turnpike (NY 25), NY 106 and NY 107 split and NY 106 continues to the northeast as Jericho-Oyster Bay Road, a four-lane divided road. Just north of NY 25A, the divider ends and NY 106 becomes Pine Hollow Road, which goes into Oyster Bay. In Oyster Bay, NY 106 is called South Street. NY 106 ends in Oyster Bay.